does semaglutide break down muscle make you lose instead of fat? Semaglutide And Bodybuilding | Can

The side effect trade-off is clear

This is the single most important point for dose-selection decisions going forward and is the reason the 9 mg arm and the new 4 mg maintenance dose are under such close scrutiny

By extending and amplifying the GLP-1 signal, semaglutide helps slow gastric emptying, reduce appetite, and improve insulin response

For primary weight loss in patients with BMI above 30, standard titration to 2.4 mg remains the evidence-based choice per the STEP trial program (Wilding et al., N Engl J Med, 2021)

On the other hand, Mounjaro is available in doses ranging from 2.5 mg to 15 mg, with the recommended starting dose being 2.5 mg